ניסיון קליני רב בטיפול במחלה קורונארית מורכבת. ניתן להתיעץ לגבי צורך בניתוח מעקפים ואפשרויות רווסקולריזציה וטיפול בצנתור. יתרונות וחסרונות של כל שיטת טיפול.

ותק

20 שנים

קופות חולים

מכבי ,פרטי

תפקיד

קרדיולוג ומצנתר בכיר

תחומי עיסוק קליני שונים

צנתורי לב אלקטיביים ודחופים (אוטמים בשריר הלב), צנתורי לב מורכבים, מחלה קורונארית מתקדמת עם חסימות כרוניות של העורקים.

טיפולים נוספים

קרדיולוגיה כללית, אי ספיקת לב.

השתלמויות

Residency, 1999-2002 Internal Medicine Sheba Medical Centre, Tel Hashomer, Israel
Residency 2003-2005 Cardiology Heart Institute, Sheba Medical Centre, Tel Hashomer, Israel
fellowship;
Mar 2007- June 2008: Clinical fellowship in interventional cardiology, Rambam Medical Centre, Haifa Israel. The fellowship in interventional cardiology lasted 15 month. Primary operator in 1600 diagnostic coronary angiograms and over 400 coronary interventions. Department of Cardiology, Rambam Health Care Campus – p.o. box 9602, Tel. 972-4-8542180, Haifa 31096 Israel.
July 2008- June 2009: Clinical fellowship in interventional cardiology, Toronto General Hospital-University Health Network, Toronto, Ontario, Canada. Primary operator in over 400 complex coronary interventions. (LM stenting, bifurcations, multiple vessel procedures, CTO, using IVUS, FFR, Rotablation, Impella support device).
July 2009- June 2010: Clinical and research fellowship in interventional cardiology, Toronto General Hospital-University Health Network, and Sunnybrook Health Sciences Centre. Toronto, Ontario, Canada. Primary operator in over 400 complex coronary interventions.
July 2010- June 2011: Clinical and research fellowship in interventional cardiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. 700 procedures (400 PCI, 300 angiographies)
July 2011- December 2012: Clinical and research fellowship in interventional cardiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
4. Board Certification
Internal medicine 2002
Cardiology 2005
ECFMG certificate March 2008 No. 0-588-931-6
(USMLE step one Dec.2007 score= 99, USMLE step 2 CK June.2007 score= 97, USMLE step 2 CS May.2008).
5. Professional Licensing
License to practice medicine, Issued by the Division of Medical Professions of the Israel Ministry of Health. No. 31734, 9.Sep.1999
Internal medicine Specialist, Israel Ministry of Health, License No. 19835, 17.Dec.2002
Cardiology Specialist, Israel Ministry of Health, license No. 22135, 19.Feb.2006
College of Physicians and Surgeons of Ontario, License to practice medicine June-2008/Dec-2011 Toronto Ontario Canada.
6. Employment History
Jan 2006 - Jan 2007: Staff cardiologist in the Heart Institute – Sheba Tel Hashomer Ramat Gan Israel. Faculty/Dept: Sackler Faculty of Medicine, Tel Aviv University, Heart Institute, Sheba Medical Centre, Tel Hashomer, Israel.
January -2012 – Senior interventional cardiologist – Department of Cardiology, Interventional cardiology unit, Barzilai Medical Center, Ashkelon, affiliated with Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
January 2012 –July 2013 - Senior cardiologist – Kupat Holim Clalit Heart failure outpatient clinic – Ganey Tikva – Israel.
June 2013 Senior cardiologist outpatient clinics –Kupat Holim Macabi -Shderot Netivot, Kiryat Malachi, Gan Yavne, Ofakim. Israel
Safety Rays LTD – Director and Main share holder.
Holds patent application (US# 13561427), leading a group of researchers and inventors designing movable shields for reducing radiation exposure and radiation safety in the catheterization Laboratory.

פרסומים מדעיים

Scientific Publications
Refereed articles in scientific journals
1. Azriel B. Osherov, Goldberg D, Atlas D. Is the neuronal voltage-sensitive calcium channel of human brain, human pancreatic beta cells and rat brain much larger than predicted by its cDNA sequence? Neurosci Lett. 1992; 147:233-235. (IF 2.055 ; JR 178/251 ; Q3 )
2. Elian D, Azriel B. Osherov, Matetzky S, Hod H, Guetta V, Feinberg M, Di Segni E. Left Ventricular Apical Ballooning: Not An Uncommon Variant Of Acute Myocardial Infarction In Women . Clinical cardiology 2006; 29:9-12 (IF 2.225 ; JR 62/125; Q2 )
3. Azriel B. Osherov, Michal Borovik-Raz , Doron Aronson, Yoram Agmon, Michael Kapeliovich, Arthur Kerner, Ehud Grenadier, Haim Hammerman, Eugenia Nikolsky, Ariel Roguin . Incidence of Early Left Ventricular Thrombus after Acute Anterior wall Myocardial Infarction in the Primary Coronary Intervention Era. Am Heart J. 2009; 157:1074-1080 (IF 4.555; JR 24/125 ; Q1; CI -19)
4. Azriel B. Osherov. Roguin A, Aronson D, Grenadier E, Kerner A, Boulus M, Kapeliovich M, Hani A, Hammerman H, Beyar R, Nikolsky E. Impact of platelet glycoprotein IIb/IIIa receptor inhibitors on renal function in patients with ST segment elevation myocardial infarction treated with primary or rescue percutaneous coronary intervention. EuroIntervention. 2009 ;5:604-9 (IF 3.758; JR 33/125; Q2; CI-3)
5. Cohen E, Azriel B. Osherov, Edry R, Sebbag A, Massalha S, Kerner A, Roguin A. Perioperative antiplatelet therapy in patients with coronary stents. Int J Cardiol. 2010;145:548-50. (IF 6.125; JR 11/125 ; Q1; CI-0 )
6. Segev A, Nili N, Azriel B. Osherov, Qiang B, Wong AJ, Pillarisetti S, Strauss BH. A perlecan-inducing compound significantly inhibits smooth muscle cell function and in-stent intimal hyperplasia: novel insights into the diverse biological effects of perlecan. EuroIntervention. 2010;6:134-40 (IF 3.758; JR 33/125; Q2; CI-2 )
7. Blich M, Zeidan-Shwiri T, Petcherski S, Azriel B. Osherov, Hammerman H. Incidence, predictors and outcome of drug-eluting stent thrombosis in real-world practice. J Invasive Cardiol. 2010; 22:461-4. (IF 0.824; JR 108/125 ; Q4 ;CI-5)
8. McKenzie DB, Talwar S, Jokhi PP, O'Kane PD, Azriel B. Osherov, Strauss B, Dahm J. How should I treat severe coronary artery calcification when it is not possible to dilate a balloon or deliver a RotaWire™? EuroIntervention. 2011;6:779-83. (IF 3.758 ; JR 33/125 ; Q2 )
9. Segev A, Nili N, Qiang B, Azriel B. Osherov, Giordano FJ, Jaffe R, Gauldie J, Sparkes JD, Fraser AR, Ladouceur-Wodzak M, Butany J, Strauss BH. Inhibition of intimal hyperplasia after stenting by over-expression of p15: A member of the INK4 family of cyclin-dependent kinase inhibitors. J Mol Cell Cardiol. 2011;50:417-25. (IF 5.218 ; JR 20/125 ; Q1; CI-2 )
10. Freixa X, Almasoud A, Azriel B. Osherov, Khan S, Wainstein R, Dzavik V. Decreased risk of stent fracture related restenosis between paclitaxel eluting stents and sirolimus eluting stents. Results of long term follow up. Catheter Cardiovasc Interv. 2012;79:559-65 (IF 2.396 ; JR 58/125 ; Q2; CI-4 )
11. Paul Fefer, Normand Robert, Beiping Qiang, Garry Liu, Nigel Munce, Kevan Anderson, Azriel B. Osherov, Michelle Ladouceur-Wodzak, Xiuling Qi, Alexander Dick, Max Weisbrod, Michelle Samuel, Jagdish Butany, Graham Wright, Bradley H. Strauss. Microvessel Formation in a Porcine Model of Coronary Arterial Chronic Total Occlusions. EuroIntervention. 2012 ;7:1444-52. (IF 3.758; JR 33/125 ; Q1; CI-0 )
12. Beiping Qiang, Jonathan Toma, Hiroko Fujii, Azriel B. Osherov, Nafiseh Nili, Paul Fefer, Michelle Samuel , Howard Leong-Poi , Bradley H. Strauss. Statin Therapy Prevents Expansive Remodelling in Venous Bypass Grafts. Atherosclerosis. 2012 ;223:106-13. (IF 3.971; JR 15/65; Q1; CI-4 )
13. Yuesong Yang, Bradley Strauss, Beiping Qiang, Azriel B. Osherov, John J Graham, Garry Liu, Xiuling Qi, Nigel R Munce, Michelle Ladouceur-Wodzk, Normand Robert, Alexander J Dick, Graham A Wright. Improvement of LV functional performance in the chronic total coronary occlusion during the late stage is associated with the extensive collateral development. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):O52 (IF 5.112; JR 21/125 ; Q1 )
14. Bradley H. Strauss, Azriel B. Osherov, Sam Radhakrishnan, GB John Mancini , Allison Manners, John D. Sparkes and Robert J. Chisholm. First-In-Man Collagenase Total Occlusion-1 (CTO-1) Trial. Circulation. 2012;125:522-8. (IF 14.948; JR 2/125; Q1; CI-3 )
15. Paul Fefer, Merril L. Knudtson, Asim Cheema, P. Diane Galbraith, Azriel B. Osherov, Sergey Yalonetsky, Sharon Gannot , Michelle Samuel, Max Weisbrod, Daniel Bierstone, John D. Sparkes , Graham J. Wright, Bradley H. Strauss. Current Perspectives on Coronary Chronic Total Occlusions-The Canadian Multicenter CTO Registry.
JACC 2012;59:991-997 (IF 15.343 ; JR 1/125 ; Q1; CI-41 )
16. Teitelbaum AA, Qi X, Azriel B. Osherov, Fraser AR., Thind A, Ladouceur-Wodzak M, Munce N, Anderson K, Qiang B, Weisbrod M, Jacobs C, Bierstone D, Erlich I, Sefton MV, Wright GA, Strauss BH. Therapeutic Angiogenesis For Facilitation of Guidewire Crossing in Experimental Arterial Chronic Total Occlusions. EuroIntervention. 2013;8:1081-9. (IF 3.758 ; JR 33/125 ; Q2; CI -0)
17. Azriel B. Osherov, Peter Seidelin, Rafael Wolff, Graham Wright, Bradley H. Strauss, Normand Robert. A Novel Technique to Reduce the Operator’s Exposure to Scattered Radiation in Transradial Coronary Procedures. Eurointervention 2013;9:757-760 (IF 3.758; JR 33/125; Q2; CI-1 ).
18. Lara Gotha , Sang Yup Lim , Azriel B. Osherov , Rafael Wolff , Beiping Qiang , Ilana Erlich , Nafiseh Nili , Sivaram Pillarisetti , Ya-Ting Chang , Phan-Kiet Tran , Karl Tryggvason , Ulf Hedin , Karin Tran-Lundmark , Suzanne L. Advani , Richard E. Gilbert , Bradley H. Strauss. Vascular Smooth Muscle Cell Response to Arterial Injury in Heparan Sulfate-Deficient Perlecan Mice: Inhibitory Role for Perlecan. American Journal of Physiology - Heart and Circulatory Physiology/ 2014 1;307:H337-45. (IF 4.012; 27/125; Q1)
19. Beiping Qiang Sang Yup Lim, Michael Lekas ,Michael A. Kuliszewski, Rafael Wolff , Azriel B. Osherov Dmitry Rudenko , Howard Leong-Poi, ,Kiet Tran , Karl Tryggvason , Ulf Hedin, Karin Tran-Lundmark , Bradley H. Strauss . Perlecan Heparan Sulfate Proteoglycan is a Critical Determinant of Angiogenesis in Response to Mouse Hind Limb Ischemia. Canadian Journal of Cardiology 2014;30:1444-5 (IF 3.94; 31/125; Q1)
20. Azriel B. Osherov, Sang Yup Lim, Jagdish Butany, Beiping Qiang, Ronen Jaffe, Ilana Erlich, Bradley H. Strauss. Effects of Intracoronary Collagenase Injection in a Porcine Model: a Safety Dose-Finding Study. J Clin Exp Cardiolog 2014, 5:7 (IF 2.03 ).
21. Avishag Laish-Farkash , Amos Katz, Ornit Cohen, Azriel B. Osherov, Sharon Bruocha, Vladimir Khalameizer. Site localization of painful lesions during radiofrequency ablation of pulmonary veins using circular multi-electrode catheters. Journal of Interventional Cardiac Electrophysiology. November 9th 2015.
22. Reuben M. Thomas, Sang Yup Lim, Beiping Qiang, Azriel B. Osherov, Nilesh R. Ghugre, Hossein Noyan, Xiuling Qi, Rafael Wolff, Michelle Ladouceur-Wodzak, Thomas A. Berk, Jagdish Butany, Mansoor Husain, Graham A. Wright and Bradley H. Strauss. Distal coronary embolization following acute myocardial infarction increases early infarct size and late left ventricular wall thinning in a porcine model. JCMR Dec 2015
Case reports
1. Leiba A, Apter S, Avni I, Azriel B. Osherov, Thaler M, Grossman E. Pyogenic liver abscess--an unusual presentation of colonic villous adenoma. Harefuah. 2003; 142:336-7, 399. Hebrew. (IF-NA ; JR-NA ; Q-NA )
2. Azriel B. Osherov. Schwammenthal E, Kuperstein R, Strahilevitz J, Feinberg M. Phialemonium Curvatum Prosthetic Valve Endocarditis with an Unusual Echocardiographic Presentation. Echocardiography. 2006; 23:503-505 (IF 2.648 ; JR 52/125 ; Q2 )
3. Azriel B. Osherov, Yuliya Azhibekov, Jamal Jafari, Ian Orlov. Anomalous Origin of the Left Internal Mammary Artery from the Aortic Arch. International journal of Cardiology 2014;171:e59-60. (IF 6.125, JR 11/125; Q1)
Editorials and invited reviews and other reviews
1. Azriel B. Osherov, Matetzky S, Beinart R, Hod H. Transient left ventricular apical ballooning (Tako-tsubo): the syndrome that mimics acute myocardial infarction. Isr Med Assoc J. 2004; 6:550-552. Review. (IF-0.903 ; JR 92/150 ; Q3 )
2. Azriel B. Osherov, Gotha L, Cheema AN, Qiang B, Strauss BH. Proteins Mediating Collagen Biosynthesis and Accumulation in Arterial Repair: Novel Targets for Anti-Restenosis Therapy. Cardiovasc Res. 2011;91:16-26 (IF 5.808 ; JR 15/125 ; Q1; CI-8 ).
Books and chapters in books
1. Azriel B. Osherov, Beiping Qiang and Bradley H. Strauss. In “Coronary artery stenosis, imaging structure and physiology”. Dr. Serruys PW, Dr. Escaned J. (Editors) Published by Europa Edition/PCR Publishing in October 2010. "Structure of chronic total occlusion".
2. Azriel B. Osherov, Bradley H. Strauss. In “Chronic Total Occlusions: A Guide to Recanalization”. Dr. Ron Waksman and Dr. Shigeru Saito (Editors) second edition. Published by Wiley-Blackwell 2011. Published Online: 8 FEB 2013. "Collagenase Plaque Digestion for Facilitating Guide Wire Crossing". Chapter 37.
3. Sergey Yalonetsky, Azriel B. Osherov, and Bradley H. Strauss. In “Chronic Total Occlusions: A Guide to Recanalization”. Dr. Ron Waksman and Dr. Shigeru Saito (Editors) second edition. Published by Wiley-Blackwell 2011. Published Online: 8 FEB 2013. "The Pathobiology of CTO". Chapter 1

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